CARPAL TUNNEL SYNDROME
- MC entrapment neuropathy of U/L, compression of median N in carpal tunnel
Anatomy
- fibro osseous canal bound by carpal bones and roofed by transverse carpal ligament
- ligament attached to scaphoid and trapezium radially, hook of hamate on ulnar side
- middle of distal carpal row bones – 10mm – narrowest point
- extends from distal wrist crease to mid palm – 5cm
- contains median N, nine Flexor tendon (FDP, FDS, FPL)
- median N gives of palmar branch to skin of palm and thenar eminence before entering canal – 5cm proximal to wrist – radial side of median n
- in canal branch to radial and ulnar br – radial br gives sensory to palmar surface of thumb and index, motor to APB, FPB(sup.head), Opp pollicis – ulnar br sensory to palmar surface of II, III, radial side of IV fingers
Etiopathogenesis
- increase in carpal tunnel pressure >20-30mm Hg – impedes epineural blood flow – nerve function impaired
- Anatomical factors
- decreased size of canal
- bony abnormalities of canal
- acromegaly
- flexion/ extension of wrist
- increased canal contents
- wrist # (colles, scaphoid)
- dislocations, subluxations
- post traumatic arthritis (osteophytes)
- aberrant muscles
- local tumors (neuroma, lipoma, ganglion)
- persistent medial artery
- hypertrophic synovium
- hematoma ( hemophilia, anticoagulation therapy)
- Physiological factors
- neuropathic
- DM – alcoholism
- inflammatory
- RA – gout – infection – nonspecific tenosynovitis
- fluid balance alterations
- pregnancy – menopause – ecclampsia – hypothyroidism – renal failure – obesity – long term hemodialysis – SLE – scleroderma – amyloidosis – Paget's disease
- external factors
- vibration – external pressure
- in children – macrodactyly, lysosomal storage disorders, family h/o
Clinical features
- numbness (MC) – paraesthesia – pain – burning sensation along median nerve
- increased at night , relieved by hanging down position
- atrophy of thenar muscles, weakness of hand muscles
Clinical tests
- Phalen's test
- elbow on table – forearm vertical – wrist flexed – 60 sec – numbness and tingling on radial digits
- sensitive > specific
- Percussion test (Tinel's sign)
- light tap- proximal to distal – along median N – tingling response in fingers
- probable CTS if + at wrist
- Durkan's compression test
- direct compression of median nerve at carpal tunnel – 30sec- paraesthesia
- most sensitive and specific
- Hand diagram
- patient marks site of pain and altered sensation on a hand diagram – finds patients perception of symptom
- markings on palmar side of radial digits
- Hand volume stress test
- hand volume measured by displacement- repeated after 7 min stress test and 10min rest
- increase of >/= 10ml
- direct carpal tunnel pressure measurement
- wick or infusion catheter placed in carpal tunnel – hydrostatic pressure in resting and provocative positioning
- >25 mm Hg resting pressure
- Reverse Phalen's test (Wormer test)
- elbow on table – forearm vertical – wrist extension – 60 sec
- Static 2 point discrimination
- failure to determined minimum 5mm separation – suggest advanced nerve dysfunction
- Moving 2 point discrimination
- minimal separation of 2 moving points applied to palmar finger tip
- normal = 4mm. <4mm – severe nerve dysfunction
- Vibrometry
- vibrometer on palmar side of digit – amplitude at 120Hz – increased to threshold of perception – compare median to ulnar b/l – asymmetry with contralateral hand or median to ulnar asymmetry of same hand
- Semme Weinstein mono filament
- monofilaments of increased diameter – touched to palmar side of digits – until patient determine which digit is touched
- nl – 2.83 or less - >2.83 indicates impairment
- Digital sensory latency and conduction velocity
- orthodromic stimulation and recording across wrist
- latency >3.5ms or asymmetry of velocity >0.5 m/s to opposite side suggestive
- Motor latency and conduction velocity
- latency >4.5ms or asymmetry of conduction velocity >1millisec
- EMG
- fibrillation potential, sharp waves, increased exertional activity
- Imaging
- X ray at 300 to extended wrist – visualized carpal tunnel
- CT – bony abnormalities
- MRI – soft tissue abnormalities
- USG
Differential diagnosis
- cervical disc herniation
- thoracic outlet syndrome
- pronator syndrome
Treatment
- Non surgical
- change of work pattern
- splint
- cause treatment like RA, DM
- NSAIDS, diuretics
- local steroid injections
- needle entry – slightly proximal to distal wrist crease – ulnar to PL to avoid median N – 1cm radial to FCU to avoid entering Guyon's canal
- needle 450 – beneath the proximal margin of TCL and directed in line with ring finger – flush of fluid into canal felt distally in mid palm
- Surgical treatment
- classic approach
- limited approaches
- double incision of Wilson
- minimal incision of Bromleg
- carpal tunnel tone through small palmar incision – Strickland
- endoscopic CTS release – single portal(Agee)– double portal (chow)
After treatment
- compression dressing and volar splint
- hand activity as soon as possible
- splint continued for comfort 2.3 wks
Unrelieved and recurrent CTS
- incomplete ligament release
- reformation of flexor retinaculum
- both needs re exploration and re release of TCL
- fibrosis or painful scar
- epineurolysis
- local muscle flaps
- local or remote free fat grafts
- excision or Z plasty of scar
- nerve wrapping or inter position materials (silicone sheet, vein wrap)
- recurrent tenosynovitis
- tenosynovectomy
- appropriate medical management ( antibiotics)
- medial or palmar cutaneous neuroma
- double crush syndrome
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