BONE GRAFT INCORPORATION
DNB MS ORTHOPEDICS QUESTION ANSWERS
- successful bone graft eventually gets incorporated into the skeletal system of host
- the graft is enveloped by host bone – replaces the donor bone tissue partially or completely
- rate of incorporation depends on : size – structure – position – fixation – genetic composition
- process of incorporation involves
- osteoconduction
- passive phenomenon
- graft acts as scaffold into which new bone can grow
- osteoinduction
- graft matrix with protein inductive factors like BMP – induce adjacent mesenchymal tissues to differentiate into osteoblasts
- osteogenesis
- direct formation of new bone by living cells of graftOrder Books Videos Notes and study material shop.orthodnb.com
Revascularisation and biological incorporation
- can be
- direct vascularisation
- creeping substitution
- never occurs by micro anastomosis with existing microvasculature
- this occurs only in cancellous bone and aided in cortical bone by removal of periosteum
- creeping substitution
- most allografts and autografts revascularize only by invasion of capillary sprouts from host bed – during resorption of graft matrix
- involves invasion of graft by osteoclast – formation of blood vessel bud – new osteons are laid down the many blood vessels that invade the graft
Stages of graft incorporation
- inflammation
- specific immune response
- revascularisation
- osteogenesis
- remodeling
Large grafts incorporation : process of serial stress fracture – resulting in graft remodeling in addition to creeping substitution
Get updates email orthoguidance@gmail.com whatsapp 9087747888
- Study Material to Pass Any Orthopaedics Exam
- Davangere Orthopaedic notes pdf
- Dawangere Ortho Notes Hard copy all volumes 2017 edition
- DNB Solved Question Bank with Answers
- Ortho Theory Exam Package
- Ortho Practical exam package
- Ortho case presentation videos
- Orthopaedic Journals
- Orthopaedic Physical Examination video Atlas
- Sion Hospital Orthopaedic Notes
- Orthopaedics Proformas and scheme of practical examination
- Orthopaedic instruments videos and extras
- Video Atlas of Human Anatomy
- Ortho Practical Exam Guide
- MRCS Package
- Orthopaedic Surgery Technique teaching videos - Trauma
- Orthopaedic Surgery Technique teaching videos - Arthroplasty
- Orthopaedic Surgery Technique teaching videos - Spine
- Orthopaedic Surgery Technique teaching videos - Shoulder Arthroscopy
- Orthopaedic Surgery Technique teaching videos - Knee Arthroscopy
- Anatomical Approach technique and exposure teaching videos
- Orthopaedic PG Course Videos
No comments:
Post a Comment